Cisplatin hearing monitoring
WebDescription; ABSTRACT. Background: The aim of this study is to evaluate the current state of ototoxicity monitoring for patients receiving cisplatin chemotherapy in an academic medical center with particular attention to how closely monitoring adheres to national ototoxicity guidelines.. Methods: Case series including retrospective medical records … WebCisplatin is used in the treatment of several childhood malignancies. Improvement in long -term survival has made the monitoring of long-term side effects more important. Nephrotoxicity and high frequency hearing loss are the most notable adverse effects of cisplatin in children. Brock et. al (1991)
Cisplatin hearing monitoring
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WebJun 21, 2024 · Hearing loss of grade 1 or higher occurred in 18 of 55 children (33%) in the cisplatin-sodium thiosulfate group, as compared with 29 of 46 (63%) in the cisplatin-alone group, indicating a 48% lower incidence of hearing loss in the cisplatin-sodium thiosulfate group (relative risk, 0.52; 95% confidence interval [CI], 0.33 to 0.81; P=0.002). WebStudy sample: Twenty-two male veterans treated with cisplatin for various cancers provided data from a total of 71 monitoring appointments. Data collection and analysis: Data were collected prospectively from one ear of each participant as designated below.
WebAug 15, 2024 · Studies of hearing loss linked to cisplatin therapy have found that anywhere between 11% and 91% of patients develop hearing loss, but more recent … WebApr 12, 2024 · In cancer patients treated with cisplatin, it would be of notable interest to include in the clinical routine the monitoring of Oct2 polymorphism, as the subjects carrying such polymorphism have a low risk to develop cisplatin-related AKI. For this reason, they would be the ideal candidates for such chemotherapy.
WebJan 27, 2024 · In cohort 1 of the IMvigor210 study, atezolizumab was studied as a first-line treatment in this group of chemotherapy-naïve cisplatin-ineligible patients, defined as those with a glomerular filtration rate (GFR) > 30 but <60 mL/min, hearing impairment, grade 2 or higher peripheral neuropathy, or ECOG performance status of ≥2 . Atezolizumab ... WebLatest version (submitted April 10, 2024) on ClinicalTrials.gov A study version is represented by a row in the table. Select two study versions to compare. One each from columns A and B. Choose either the "Merged" or "Side-by-Side" comparison format to specify how the two study versions are to be displayed.
WebDec 31, 2024 · Monitoring hearing during chemotherapy Because of this risk for hearing loss, if you are being treated with a platinum-based chemotherapy drug it’s important that you keep an eye (or an ear) on your hearing. Hearing loss may be accompanied by tinnitus, which often manifests as a ringing in the ears.
WebApr 13, 2024 · Cisplatin therapy is used in a variety of treatment protocols, but it is most commonly used in gynecological (ovarian and cervical) and head and neck cancers. In … sims 4 spa day ccrch staph clearanceWebMar 29, 2024 · In conclusion, cisplatin-induced ototoxicity remains an essential concern in the modern era. Implementing system-wide ototoxicity monitoring programs and leveraging technology using built-in ordering prompts may improve hearing outcomes. sims 4 spa chairWebOct 20, 2024 · Cumulative dose of cisplatin is an important predictor of development of ototoxicity. Baseline and periodic audiometric monitoring could detect ototoxicity early which leads to possible... rch staphWebInstructions for use Sinupret recommends taking 2 drops or 50 drops of the drug three times a day. Dragee swallowed whole, without biting and squeezing a small volume of liquid. … rch staph eradication therapyWebFeb 11, 2024 · Cisplatin is a highly effective chemotherapeutic drug used against a wide range of childhood and adult cancers, but cisplatin crosses into the cochlea, which often results in permanent sensorineural cisplatin-induced hearing loss (CIHL). sims 4 spa day reviewWebCisplatin is a bedrock of cancer management and one of the most used chemotherapeutic agents in the treatment of germ cell, lung, bladder, ovarian, and head and neck cancers. Approximately 500,000 patients diagnosed annually with these cancer types in the United States could be candidates for treatment with cisplatin. There is a 5-fold increase in the … sims 4 spa day hair