TīmeklisTocilizumab (TCZ) is a humanized antibody against the soluble IL-6 receptor (sIL-6R) and membrane-bound IL- 6 receptor (mIL- 6R), blocking these receptor complexes and preventing IL-7 transmembrane signaling. Overactivity of IL-6 plays a very important role in both the exsudative and proliferative phase of rheumatoid inflammation, joint … Tīmeklis2024. gada 1. apr. · The top hub genes such as interleukin 6, jun proto-oncogene, chemokine receptor 5, epidermal growth factor receptor, were identified from the protein-protein interaction network and may be used as potential targets for rheumatoid arthritis treatment. OBJECTIVE The aim of this study was to identify potential key …
Identification of Key Genes and Pathways in Rheumatoid Arthritis …
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