Smurf2 epd0424_6_h08
Webepd0424_6_h08 Find Mice Using the International Mouse Strain Resource ( IMSR ) Mouse lines carrying: Smurf2 tm1b(EUCOMM)Wtsi mutation (0 available); any Smurf2 mutation ( … Web26 Jun 2024 · The variant calls can alternatively be generated by independently running each of the five callers, but we recommend using bcbio-nextgen for ease of use and full compatibility with SMuRF2 and its input data requirements.. 2.3 Test Dataset. SMuRF2 is pre-loaded with a test dataset that comprises input VCF files generated from a subset of …
Smurf2 epd0424_6_h08
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WebSmurf2 interacts with Smad7 to suppress TGF-β-mediated liver fibrosis through the ubiquitin-dependent degradation of TβRI during the early period of liver fibrosis. … Web21 Sep 2024 · F The protein expression of SMURF2 and YY1 in cells overexpressing SMURF2 assayed by Western blot. *p < 0.05 vs. oe-NC-treated cells; G Co-IP analysis of …
Webcing effect of Smurf2 expression at the protein level Figure 1 Smurf2 is upregulated in human breast cancer cell lines. (A) Smurf2 was found to be specifically upregulated in MDA-MB-231 cell line compared to other breast cancer cell lines. An untransformed immortalized cell line, MCF-10A was used as the control. β-actin was used to WebSmurf2 tm1b(EUCOMM)Wtsi: Name: SMAD specific E3 ubiquitin protein ligase 2; targeted mutation 1b, Wellcome Trust Sanger Institute: MGI ID: MGI:5548518: Gene: Smurf2 …
Web23 Nov 2024 · A previous study reported that Smurf2 ubiquitinates and promotes the degradation of Smurf1. 26 A possible reason for the increased Smurf1 expression observed in this study is that Smurf1... Web1 Mar 2001 · Negatively regulates TGFB1-induced epithelial-mesenchymal transition and myofibroblast differentiation ( PubMed: 30696809 ). (Microbial infection) In case of …
Web5 Aug 2005 · Smurf2 residues 269-748 containing the second and third WW domains and the HECT domain was expressed in E. coli BL21 (DE3) as a poly histidine-tagged fusion using the pProEX HTa vector, whereas full-length wild-type and mutant versions of Smurf2, Smad7 and UbcH7 were expressed as GST-fusions in E. coli BL21 using the pGex4T1 …
http://www.informatics.jax.org/allele/MGI:4431726 greybeardman.comWeb5 Oct 2015 · As SMURF2 is a potent inhibitor of TGF-β activity we investigated whether introducing a K734R mutant of SMURF2 into the TGF-β responsive metastatic breast … greybeard live resin terp sauceWebGateway Donor vector containing SMURF2 , part of the Target Accelerator Plasmid Collection. Depositor. Jesse Boehm, William Hahn, David Root. Article. Kim et al Cancer … fidelity adv diversified stock cl o 6 tickerWeb11 Jan 2024 · Glioma stem cells (GSCs) contribute to the pathogenesis of glioblastoma, the most malignant form of glioma. The implication and underlying mechanisms of SMAD specific E3 ubiquitin protein ligase 2 (SMURF2) on the GSC phenotypes remain unknown. We previously demonstrated that SMURF2 phosphorylation a … greybeard live resin terp slushWeb21 Mar 2024 · SMURF2 (SMAD Specific E3 Ubiquitin Protein Ligase 2) is a Protein Coding gene. Diseases associated with SMURF2 include Cockayne Syndrome and Breast Cancer . … fidelity adv freedom 2030-cl igreybeard long term rentalsWeb25 Mar 2013 · Expression of the E3 ubiquitin ligase, Smurf2, had the most significant effect on EZH2 protein levels compared with the other E3 ubiquitin ligases (Mdm2, Fbw7, Cbl-b, Skp2 and Smurf1), and Smurf2-mediated decrease in EZH2 was restored by the addition of a proteasome inhibitor, MG132 (Supporting Information Fig S2), suggesting that Smurf2 is … fidelity adv freedom 2035-cl i