The matricellular protein sparc
Splet28. feb. 2024 · SPARC and stabilin 1 are a protein and a receptor, respectively, which bind together and are expressed by macrophages in inflammatory conditions. Citation 36 SPARC is a secreted matricellular protein that promotes cellular deadhesion and motility in wound healing, carcinogenesis, and inflammation. Splet12. avg. 2024 · SPARC is a matricellular protein that is constitutively expressed in many tissues, including adipose tissues. Increased SPARC is associated with obesity, diabetes, …
The matricellular protein sparc
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Splet15. jan. 2013 · Matricellular proteins have been classified as a family of non-structural matrix proteins capable of modulating a variety of biological processes within the …
SpletThe concept of a matricellular protein was first proposed by Paul Bornstein in the mid-1990s to account for the non-lethal phenotypes of mice with inactivated genes encoding thrombospondin-1, tenascin-C, or SPARC. It was also recognized that these extracellular matrix proteins were primarily counter or de-adhesive. Splet01. nov. 2003 · It is hypothesized that TGF-β2 upregulates SPARC expression in human TM through Smad-dependent (Smad2/3) or -independent (p38) signaling pathways, and SPARC may be a downstream regulatory node of TGF -β2-mediated IOP elevation. Expand 34 PDF View 1 excerpt, cites background Save Alert
Splet15. jan. 2024 · SPARC, a secreted matricellular protein, is over-expressed in the liver under chronic injury. Contribution of SPARC accumulation to disease severity is largely unknown in NAFLD. Splet26. jun. 2008 · SPARC is a prototypical matricellular protein that modulates interactions between cell surface and ECM molecules, thus controlling cell adhesion, differentiation, and angiogenesis [24– 26, 39]. Automated computer-assisted alignment [ 12 , 17 ] of all sequences isolated in the library selection against the SPARC amino acid sequence …
Splet25. mar. 2008 · SPARC (secreted protein, acidic and rich in cysteine) is a matricellular protein that is highly expressed during development, tissue remodeling, and repair. SPARC produced by olfactory ensheathing cells (OECs) can promote axon sprouting in …
Splet152-291: 9.88e-63: EF-hand, extracellular calcium-binding (EC) motif, found in secreted protein acidic and rich in cysteine (SPARC); SPARC, also termed basement-membrane … chili\u0027s drinks menuSplet30. apr. 2015 · The discovery that SPARC, a matricellular protein involved in tumour cell invasion and survival 20, and endothelial barrier function 21, was 10-fold more abundant in metastatic melanoma cell... chili\u0027s ebogSplet07. okt. 2009 · SPARC (secreted protein acidic and rich in cysteine), also known as osteonectin and BM-40, is a multifunctional secreted glycoprotein that exemplifies the matricellular class of proteins (Framson and Sage 2004 ). chili\u0027s elk groveSplet152-291: 9.88e-63: EF-hand, extracellular calcium-binding (EC) motif, found in secreted protein acidic and rich in cysteine (SPARC); SPARC, also termed basement-membrane protein 40 (BM-40), or osteonectin (ON), is a prototypic collagen-binding matricellular protein that is essential for embryo development in invertebrates and highly expressed in … chili\u0027s durant oklahomaSpletterm ‘matricellular’ was introduced to explain the unusual diversity of functions that were beginning to be recognized in proteins such as thrombospondin-1(TSP-1), SPARC, and tenascin-C. (Sage and Bornstein 1991; Bornstein 1995). The intent of segregating this subclass of secreted proteins was to emphasize that the extracellular environment ... chili\\u0027s east brunswick njSplet22. jun. 2001 · One of the genes revealed codes for SPARC, a matricellular protein that it thought to modulate cell-matrix interaction (27). We have demonstrated that SPARC is a … chili\u0027s dry rub ribsSpletDOI: 10.1007/s10555-008-9146-7 Corpus ID: 10829746; The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host @article{Podhajcer2008TheRO, title={The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host}, author={Osvaldo L. Podhajcer and … chili\\u0027s edmond oklahoma